Really exciting： Motif Neurotech just got FDA clearance to trial its DOT implant for treatment-resistant depression， and the key detail is where it sits： on top of the skull， not inside the brain.

That alone could change the calculus for patients who need neurostimulation but dread the surgery.

For the millions stuck cycling through medications without relief， the ambition here goes beyond stimulation. Think continuous glucose monitor， but for depression： real-time， adjustable， and precise.