加速遗传线索以逆转细胞衰老
阅读原文· deepmind.google生物学家利用Co-Scientist这一工具，成功发现能够使人类细胞年轻化的新型因子。该研究通过人工智能加速了遗传线索的探索过程，为逆转细胞衰老领域提供了新的关键因素。这一发现标志着利用技术手段干预生物老化进程取得了实质性进展。
Co-Scientist: Accelerating research on cellular aging — Google DeepMind
May 19, 2026 Science
Fast-tracking genetic leads to reverse cellular aging
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Two of the biggest bottlenecks in aging research are deciding which genetic pathways to test and making sense of the vast data those experiments produce. Biologists Omar Abudayyeh and Jonathan Gootenberg are using Co-Scientist to help them blast through both.
Their lab runs huge genetic screens that flip thousands of genes on or off then reads how cells respond to these changes. The goal is to find changes that push cells away from senescence – a damaged state linked to aging – and toward a youthful state in tissues such as skin, hair, and muscle.
Co-Scientist is helping on two fronts. First, it generates leads. When the team asked it to trawl the scientific literature for factors that might reverse aging, it scanned tens of thousands of papers, considered a multitude of hypotheses, and ultimately proposed more than 20 novel, plausible genetic factors to test. Lab tests validated a couple Co-Scientist’s hypotheses, with its recommended factors successfully driving cells into a younger state with improved overall function.