Notes2Skills:从实验笔记到具有确定性意识的科学AI智能体技能
阅读原文· arxiv.orgNotes2Skills是一个两阶段框架,旨在将实验笔记转化为可验证的科学AI智能体技能,同时保留作者对观测结果的不确定性。在七个条件和三次湿实验室实验中,Notes2Skills是唯一既不会将不确定的笔记误认为明确指令、也不会丢弃明确指令的配置。研究表明,确定性保留是连接实验笔记与可靠智能体技能之间缺失的关键环节,为开发更安全的AI合作科学家系统提供了新路径。
Scientific discovery workflows usually contain and rely heavily on lab notes, where researchers record observations, interpret uncertain results, and plan follow-up experiments. Such informative lab notes preserve evolving scientific reasoning and author uncertainty, rather than polished final results exhibited in publications, providing a valuable opportunity for AI to engage in scientific exploration at a more comprehensive and deeper level. However, most prior work on scientific text focuses on papers, protocols, or structured databases, leaving informal laboratory notes underexplored as inputs to AI agents for science. This gap matters because lab notes often intermingle validated observations, tentative judgments, and possible experimental next steps within the same passage. If these signals are conflated, an AI agent may mistake uncertain scientific judgments for confirmed conclusions or executable actions. To this end, we present Notes2Skills, a two-stage framework for turning lab notebooks into verifiable skills for scientific AI agents while preserving the author's certainty. Across seven conditions and three wet-lab sessions, Notes2Skills is the only configuration that neither mistakes uncertain notes for firm instructions nor discards firm ones. We show that certainty preservation is the missing piece between lab notebooks and reliable agent skills, opening a path toward safer AI co-scientist systems.